Lidocaine HCl Injection 2% by International Medication Systems is a sterile, prefilled syringe solution designed for rapid, effective local anesthesia and acute arrhythmia management. Each 5 mL syringe contains 100 mg of lidocaine hydrochloride, prepared for prompt use in a range of clinical settings. The Luer-Jet Luer-Lock system ensures precise administration and reduces contamination risks, offering healthcare professionals a reliable tool for achieving both peripheral nerve blocks and systemic antiarrhythmic effects.
Product Details and Features
Concentration: 2% Lidocaine Hydrochloride (20 mg/mL)
Volume: 5 mL prefilled syringe
Total Lidocaine Content: 100 mg per syringe
Form: Sterile, single-use syringe
Design: Luer-Jet Luer-Lock for secure connectivity
Manufacturer: International Medication Systems, a leader in emergency medication production
Mechanism of Action
Lidocaine functions primarily as a local anesthetic. It stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of nerve impulses, primarily sodium ion influx, thereby producing its anesthetic effect. Additionally, when administered intravenously for arrhythmias, lidocaine acts by shortening the action potential and decreasing myocardial excitability, effectively suppressing abnormal cardiac rhythms without significantly affecting the renal or central nervous system function at therapeutic levels.
Directions for Use
1. Administration: Available for both local and intravenous application.
2. Preparation: Inspect the solution for clarity and absence of particulates. Do not use if discolored or containing particles.
3. Instructions: Connect using the Luer-Lock system to reduce contamination risks. Administer according to healthcare provider guidance.
4. Dosing: Dosing is individualized based on the anesthetic requirement or arrhythmic condition and the patient's health status.
Specific dosing protocols may differ based on clinical guidelines and should always be referenced from current medical protocols.
Warnings
- Hypersensitivity: Contraindicated in patients with known hypersensitivity to amide-type local anesthetics.
- Systemic Toxicity: Overdosage or intravascular injection can lead to CNS or cardiovascular toxicity.
- Bradycardia and Heart Block: Caution in patients with severe heart block or bradycardia.
- Hepatic Impairment: Use cautiously in patients with impaired liver function due to altered metabolism of lidocaine.
Side Effects
Lidocaine use can result in:
- Local: Injection site irritation, swelling, or erythema
- Systemic: Dizziness, tinnitus, or blurred vision
- CNS: Seizures at high plasma levels, altered mental status
- CVS: Hypotension, bradycardia, or cardiac arrest with overdosage